Integrating proteomic and clinical data to discriminate major psychiatric disorders: Applications for major depressive disorder, bipolar disorder, and schizophrenia
- Journal
- Clinical and Translational Medicine
- Vol
- 12
- Year
- 2022
- Link
- https://doi.org/10.1002/ctm2.929 1058회 연결
Dear editor,
We report that integrating proteomic and clinical data enables objective differentiation between major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SCZ). These major psychiatric disorders are associated with mortality and life-long disability.1 However, objective discrimination of these disorders remains a formidable challenge. Thus, this study aimed to distinguish MDD, BD, and SCZ by integrating targeted/untargeted proteomic data obtained from liquid chromatography-mass spectrometry (LC-MS) and clinical data.